Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives

Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives

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The isatin derivatives, Schiff bases, canine spectra kc 3 intranasal single dose were synthesized by the reaction of isatin and various substituted primary amines and characterized by several spectroscopic methods.Investigation of the antimicrobial activity of the synthesized compounds was performed by the agar dilution method, against different strains of bacteria and one fungi.The antioxidative activity of the synthesized compounds was also determined.Some of the compounds have shown the significant activity against the selected ultrastar dc hc550 strains of microorganisms and the antioxidative activity.

[Projekat Ministarstva nauke Republike Srbije, br.172013 i III 46010].